Basic Research Studies / Ongoing Pilot Projects
There is a strong commitment within the Center to basic research regarding the underlying mechanisms of Alzheimer's Disease and related disorders, and how this may translate into effective treatment.
The following basic research studies are underway:
Beta-amyloid modulation role of BACE1 and BACE2
Modeling an anti-amyloid therapy for AD
Neuronal activity-dependent secretion of A-beta and immediate early genes
Nicastrin and gamma secretase in AD
Synapse formation in vitro
The roles of A-beta, tau, and synaptic loss in early AD
Transynaptic cortical apoptosis mechanisms and therapy
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