Johns Hopkins Medicine

Alzheimer's Disease Research Center

Dr. Lyketsos

Constantine G. Lyketsos, M.D., M.H.S.

ADRC Associate Director
Clinical Core Leader
Education Core Co-Leader

Dr. Lyketsos is currently Chief of Psychiatry at the Johns Hopkins Bayview Medical Center. He is also the Elizabeth Plank Althouse Professor for Alzheimer's Research.

Dr. Lyketsos' research interests include the epidemiology of dementia, the epidemiology and treatment of neuropsychiatric disorders in dementia, and the etiology and effect of mood disorders occurring in patients with Alzheimer's.


  • Porsteinsson AP, Drye LT, Pollock BG, Devanand DP, Frangakis C, Ismail Z, Marano C, Meinert CL, Mintzer JE, Munro CA, Pelton G, Rabins PV, Rosenberg PB, Schneider LS, Shade DM, Weintraub D, Yesavage J, Lyketsos CG. Effect of citalopram on agitation in Alzheimer disease: the CitAD randomized clinical trial. JAMA. 2014; 311: 682-691.
  • Trzepacz PT, Cummings J, Konechnik T, Forrester TD, Chang C, Dennehy EB, Willis BA, Shuler C, Tabas LB, Lyketsos C. Mibampator (LY451395) randomized clinical trial for agitation/aggression in Alzheimer's disease. Int Psychogeriatr. 2013; 25: 707-719.
  • Tighe S, Oishi K, Mori S, Smith GS, Albert M, Lyketsos C, Mielke M. Diffusion tensor imaging of neuropsychiatric symptoms in mild cognitive impairment and Alzheimer's dementia. J Neuropsychiatry Clin Neurosci 2012; 24: 484-488.
  • Rosenberg P, Mielke M, Appleby B, Oh E, Leotsakos J, Lyketsos C. Neuropsychiatric symptoms in MCI subtypes: the importance of executive dysfunction. Int J Geriatr Psychiatry 2011; 26: 364-372.