Johns Hopkins Medicine

Alzheimer's Disease Research Center

Shanthini Sockanathan, D.Phil.

Shanthini Sockanathan, D.Phil.

Associated Investigator

Dr. Shanthini Sockanathan is an associate professor of neuroscience at the Johns Hopkins University School of Medicine. Her research focuses on mechanistic control of neuronal and glial differentiation and function.


  • Park S, Lee C, Sabharwal P, Zhang M, Meyers C, Sockanathan S. "GDE2 Promotes Neurogenesis by Glycosylphosphatidylinositol-Anchor Cleavage of Reck". Science 339:324-339. 2013
  • Rodriguez M, Choi J, Park S, Sockanathan S. "Gde2 regulates cortical neuronal identity by controlling the timing of cortical progenitor differentiation". Development 2012 Oct; 139(20):3870-9. Epub 2012 Sep 5
  • Sabharwal P, Lee C, Park S, Rao M, Sockanathan S. "GDE2 regulates subtype-specific motor neuron generation through inhibition of Notch signaling". Neuron. 2011 Sep 22; 71(6):1058-70. Epub 2011 Sep 21.
  • Periz G, Yan Y, Bitzer ZT, Sockanthan S. "GDP-bound Galphai2 regulates spinal motor neuron differentiation through interaction with GDE2". Dev Biol. 2010 May 1; 341(1):213-21. Epub 2010 Mar 1.
  • Ye Y, Sabharwal P, Rao M, and Sockanathan S. "The Antioxidant Enzyme Prdx1 Controls Neuronal Differentiation by Thiol-Redox-Dependent Activation of GDE2". Cell 138:1209-1221.