 |
||
 |
 |
 |
|
|
| Our Team | |
Barbara Crain, M.D., Ph.D.
Co-Investigator Email Address: bcrain@jhmi.edu Dr. Crain’s research interests concern the patterns and mechanisms of neuronal vulnerability in different disease states. Most of her current work is in the area of neurodegenerative disease and stroke. 
Rudow G, O’Brien R, Savonenko A, Resnick S, Zonderman A, Pletnikova O, Marsh L, Dawson T, Crain BJ, West M, Troncoso J. Morphometry of the human subtantia nigra in ageing and Parkinson’s disease. Acta Neuropathologica 2008; 115: 461-470. Iacono D, O Brien R, Resnick SM, Zonderman AB, Pletnikova O, Rudow G, An Y, West MJ, Crain BJ, Troncoso JC. Neuronal hypertrophy in asymptomatic Alzheimer disease. J. Neuropathol Exp Neurol, 2008; 67: 578-589 Troncoso J, Zonderman A, Resnick S, Crain BJ, Pletnikova O, O’Brien R. Effect of infarcts on dementia in the Baltimore Longitudinal Study of Aging. Ann Neurol, 2008; 64: 168-176. Li T, Wen H, Brayton C, Laird FM, Ma G, Peng S, Placanica L, Wu TC, Crain BJ, Price DL, Eberhart CG, Wong PC. Moderate reduction of y-secretase attenuates amyloid burden and limits mechanism-based liabilities. J Neurosci 2007;27: 10849-10859.
Mikolaenko I, Pletnikova O, Kawas C, O’Brien R, Resnick S, Crain BJ, Troncoso J. Alpha-synuclein lesions in normal aging, Parkinson’s disease and Alzheimer’s disease: evidence from the Baltimore Longitudinal Study of Aging (BLSA). J Neuropathol Exp Neurol, 2005; 64: 156-162.
|
