Lee J. Martin, Ph.D.
Co-Investigator
Email Address: martinl@jhmi.edu
Dr. Martin’s major research interest is cell death signaling in neurological disease. He uses animal and cell models of human neurodegenerative disease and the techniques of molecular neuropathology / neurobiology to unravel the mechanisms of neurodegneration.
Chang Q, Martin LJ. Motorneuron subtypes show specificity in glycine receptor channel abnormalities in a transgenic mouse model of amyotrophic lateral sclerosis. Channels 2011; 5: 299-303. O’Brien R, Resnick S, Zonderman A, Ferucci L, Crain B, Pletnikova O, Rudow G, Iacono D, Riudavets M, Driscoll I, Price D, Martin L, Troncoso J. Neuropathologic studies of the Baltimore Longitudinal Study of Aging (BLSA). J Alzheimers Dis 2009; 665-675. Laird F, Farah M, Ackerly S, Hoke A, Maragakis N, Rothstein J, Griffin J, Price DL, Martin LJ, Wong PC. Motor neuron disease occurring in a mutant dynactin mouse model is characterized by defects in vasicular trafficking. J. Neurosci 2008; 28: 1997-2005.
Martin LJ, Pan Y, Price A, Sterling W, Copeland N, Jenkins N, Price DL, Lee MK. Parkinson’s disease alpha-synuclein transgenic mice develop neuronal mitochondrial degeneration and cell death. J Neurosci 2006; 26: 41-50.
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