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| Our Team | |
Alena Savonenko, M.D., Ph.D.
Email Address: asavone1@jhmi.edu Dr. Savonenko’s research interests include: neurobiological mechanisms of learning and memory, animal behavioral models, and neurobiological mechanisms of normal aging and neurodegenerative disorders, such as Alzheimer’s disease. 
Oh ES, Savonenko AV, King JF, Fangmark Tucker S, Rudow GL, Xu G, Borchelt DR, Troncoso JC. Amyloid precursor protein increases cortical neuron size in transgenic mice. Neurobiol Aging, in press. Savonenko A, Melnikova T, Laird F, Stewart K, Price D, Wong P. Alteration of BACE-1-dependent NRG1/ErbB4 signaling and schizophrenia-like phenotypes in BACE-1 null mice. Proc Natl Acad Sci, 2008; 105: 5585-5590. Rudow G, O’Brien R, Savonenko A, Resnick S, Zonderman A, Pletnikova O, Marsh L, Dawson T, Crain BJ, West M, Troncoso J. Morphometry of the human subtantia nigra in ageing and Parkinson’s disease. Acta Neuropathologica 2008; 115: 461-470. Melnikova T, Savonenko A, Wang Q, Liang X, Hand T, Wu L, Kaufman W, Vehmas A, Andreasson K. Cycloxygenase-2 activity promotes cognitive deficits but not increased amyloid burden in a model of Alzheimer’s disease in a sex-dimorphic pattern. Neurosci, 2006; 141: 1149-1162.
Savonenko A, Xu G, Melnikova T, Morton J, Gonzales V, Wong PC, Price DL, Tang F, Markowska A, Borchelt DR. Episodic-like memory deficits in the APPswe/PS1dE9 mouse model of Alzheimer’s disease: relationships to beta-amyloid deposition and neurotransmitter abnormalities. Neurobiol Dis 2005; 18: 602-617.
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