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| Our Team | |
Gwenn Smith, Ph.D. Email Address: gwsmith95@jhmi.edu Dr. Smith’s research is primarily focused on using functional imaging, particularly positron emission tomography (PET), to understand the regulation of monoamine systems in the pathophysiology and treatment response in affective and cognitive disorders. She is currently examining the role of monoamine dysregulation in geriatric depression and Alzheimer’s disease. 
Smith GS, Kahn A, Sacher J, Rusjan P, van Emeren T, Flint A, Wilson A. Serotonin transporter occupancy and the functional neuroanatomic effects of citalopram in geriatric depression. Am J Geriatr Psychiatry 2011 Epub ahead of print Smith GS, Workman C, Kramer E, Hermann C, Ginsberg R, Ma Y, Dhawan V, Chaly T, Eidelberg D. The relationship between the acute cerebral metabolic response to citalopram and chronic citalopram treatment outcome. Am J Geriatr Psychiatry 2011; 19: 53-63. Diaconescu A, Kramer E, Hermann C, Ma Y, Dhawan V, Chaly T, Eidelberg D, McIntosh A, Smith G. Distinct functional networks associated with improvement of affective symptoms and cognitive function during citalopram treatment in geriatric depression. Hum Brain Mapp 2011; 32: 1677-1691. Smith GS, Kramer E, Ma Y, Hermann C, Chawan V, Chaly T, Eidelberg D. Cholinergic modulation of the cerebral metabolic response to citalopram in Alzheimer’s disease. Brain 2009; 132: 392-401.
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