Alena Savonenko, M.D., Ph.D.
Email Address: email@example.com
Dr. Savonenko’s research interests include: neurobiological mechanisms of learning and memory, animal behavioral models, and neurobiological mechanisms of normal aging and neurodegenerative disorders, such as Alzheimer’s disease.
Tabatadze N, Savonenko A, Song H, Banaru V, Chu M, Haughey N. Inhibition of neutral sphingomyelinase-2 perturbs brain sphingolipid and spatial memory in mice. J Neurosci Res 2010 88: 2940-2951.
Oh ES, Savonenko AV, King JF, Fangmark Tucker S, Rudow GL, Xu G, Borchelt DR, Troncoso JC. Amyloid precursor protein increases cortical neuron size in transgenic mice. Neurobiol Aging 2009; 30:1238-1244.
Savonenko A, Melnikova T, Laird F, Stewart K, Price D, Wong P. Alteration of BACE-1-dependent NRG1/ErbB4 signaling and schizophrenia-like phenotypes in BACE-1 null mice. Proc Natl Acad Sci, 2008; 105: 5585-5590.
Melnikova T, Savonenko A, Wang Q, Liang X, Hand T, Wu L, Kaufman W, Vehmas A, Andreasson K. Cycloxygenase-2 activity promotes cognitive deficits but not increased amyloid burden in a model of Alzheimer’s disease in a sex-dimorphic pattern. Neurosci, 2006; 141: 1149-1162.
Savonenko A, Xu G, Melnikova T, Morton J, Gonzales V, Wong PC, Price DL, Tang F, Markowska A, Borchelt DR. Episodic-like memory deficits in the APPswe/PS1dE9 mouse model of Alzheimer’s disease: relationships to beta-amyloid deposition and neurotransmitter abnormalities. Neurobiol Dis 2005; 18: 602-617.
Primary Appointment in Pathology